HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: ZN263 (O14978)
Zinc finger protein 263 (Zinc finger protein FPM315) (Zinc finger protein with KRAB and SCAN domains 12)
Gene: ZNF263

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1030 Hs			1 683
+	Hs
		161816 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN263_HUMAN (1-683): 0: 705: 100.00
+	Hs
		980477 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN480_HUMAN (191-683): 0: 572: 33.83
+	Hs
		161850 ANR52_HUMAN (5-197): 6.34e-34: 143: 17.24		ZN263_HUMAN (1-683): 0: 705: 100.00
+	Hs
		980426 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZSCA2_HUMAN (119-683): 0: 541: 34.09
+	Hs
		980560 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN624_HUMAN (169-682): 1.87e-179: 534: 32.12
+	Hs
		161768 ANR17_HUMAN (123-866): 2.56e-17: 89.9: 10.46		ZN263_HUMAN (1-683): 0: 705: 100.00
+	Hs
		161842 ANKH1_HUMAN (129-877): 2.32e-16: 86.9: 9.34		ZN263_HUMAN (1-683): 0: 705: 100.00
+	Hs
		980473 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN483_HUMAN (237-628): 1.01e-139: 428: 31.98
+	Hs
		563266 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN708_HUMAN (142-578): 2.94e-133: 405: 25.34
+	Hs
		259990 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN253_HUMAN (434-683): 5.16e-120: 369: 48.00
+	Hs
		980498 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN419_HUMAN (380-628): 8.16e-72: 243: 47.79
+	Hs
		980381 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZKSC8_HUMAN (132-405): 3.47e-48: 180: 13.62
+	Hs
		887229 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN445_HUMAN (93-431): 4.3e-36: 147: 11.01
+	Hs
		275736 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN189_HUMAN (370-540): 2.6e-33: 137: 42.29
+	Hs
		563705 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZKSC1_HUMAN (507-683): 1.43e-33: 137: 46.24
+	Hs
		980472 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN431_HUMAN (98-375): 2.39e-25: 113: 8.74
+	Hs
		549241 ANR50_HUMAN (22-935): 8.69e-65: 241: 13.09		ZN250_HUMAN (257-429): 9.24e-36: 144: 16.48
+	Hs
		980539 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN430_HUMAN (98-375): 1.71e-21: 100: 8.68
+	Hs
		67863 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZN724_HUMAN (230-379): 9.97e-16: 83: 10.90
+	Hs
		977952 NOTC2_HUMAN (8-636): 7.56e-77: 279: 18.38		ZNF92_HUMAN (122-339): 7.02e-10: 64.2: 8.07