HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	21115810
Identification Methods	affinity chromatography technology, pull down, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1030 Hs			1 852
+	Hs
		166858 ANR28_HUMAN (1-175): 3.5e-38: 156: 20.99		KDM1A_HUMAN (1-852): 0: 936: 100.00
+	Hs
		232331 ANR52_HUMAN (5-197): 6.34e-34: 143: 17.24		KDM1A_HUMAN (1-852): 0: 936: 100.00
+	Hs
		231904 ANR17_HUMAN (123-866): 2.56e-17: 89.9: 10.46		KDM1A_HUMAN (1-852): 0: 936: 100.00
+	Hs
		232304 ANKH1_HUMAN (129-877): 2.32e-16: 86.9: 9.34		KDM1A_HUMAN (1-852): 0: 936: 100.00