HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1030 Hs			1 173
+	Hs
		161263 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		CC14B_HUMAN (5-149): 7.21e-38: 137: 24.84
+	Hs
		161378 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		CDKN3_HUMAN (27-171): 2.36e-28: 106: 22.29
+	Hs
		239422 ANR50_HUMAN (22-935): 8.69e-65: 241: 13.09		CC14B_HUMAN (5-149): 7.21e-38: 137: 24.84
+	Hs
		890841 TNKS2_HUMAN (1-611): 2.38e-60: 227: 12.05		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		310043 TNKS1_HUMAN (1-682): 9.92e-60: 225: 12.67		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		310061 TNKS1_HUMAN (1-682): 9.92e-60: 225: 12.67		TENS2_HUMAN (4-168): 8.07e-39: 142: 13.74
+	Hs
		1167720 MIB1_HUMAN (41-304): 3.48e-51: 198: 21.75		TPTE2_HUMAN (6-168): 1.11e-42: 150: 15.85
+	Hs
		1021808 ANR52_HUMAN (5-197): 6.34e-34: 143: 17.24		TP4A2_HUMAN (4-172): 8.42e-53: 167: 77.52
+	Hs
		166860 ANR28_HUMAN (1-175): 3.5e-38: 156: 20.99		CC14B_HUMAN (5-149): 7.21e-38: 137: 24.84
+	Hs
		56494 ANR28_HUMAN (1-175): 3.5e-38: 156: 20.99		PTPC1_HUMAN (2-171): 8.66e-36: 133: 20.73
+	Hs
		161735 KDIS_HUMAN (1-162): 1.37e-32: 139: 19.10		GAK_HUMAN (9-151): 1.05e-38: 141: 17.42
+	Hs
		239365 ANR52_HUMAN (5-197): 6.34e-34: 143: 17.24		CC14B_HUMAN (5-149): 7.21e-38: 137: 24.84
+	Hs
		239362 ANR44_HUMAN (159-427): 1.52e-19: 96.9: 13.73		CC14B_HUMAN (5-149): 7.21e-38: 137: 24.84
+	Hs
		985185 ANKH1_HUMAN (129-877): 2.32e-16: 86.9: 9.34		DUS2_HUMAN (2-154): 7.14e-31: 115: 18.71
+	Hs
		276208 PSD10_HUMAN (37-174): 3e-09: 60.5: 34.29		DUS9_HUMAN (18-168): 1.2e-32: 121: 19.36