HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25609649, 20195357
Identification Methods	affinity chromatography technology, tandem affinity purification, display technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1030 Hs			1 380
+	Hs
		161303 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		JUNB_HUMAN (85-215): 3.19e-25: 106: 19.86
+	Hs
		161287 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		JUN_HUMAN (48-215): 1.19e-23: 102: 16.47
+	Hs
		1231010 PP16A_HUMAN (2-310): 2.43e-80: 273: 36.11		BATF2_HUMAN (132-321): 5.68e-30: 118: 17.16
+	Hs
		257539 ANR17_HUMAN (123-866): 2.56e-17: 89.9: 10.46		FOS_HUMAN (1-380): 1.68e-84: 263: 100.00
+	Hs
		345485 ANKH1_HUMAN (129-877): 2.32e-16: 86.9: 9.34		FOS_HUMAN (1-380): 1.68e-84: 263: 100.00
+	Mm
		1194498 DAPK1_MOUSE (11-307): 7.15e-57: 217: 21.94		CR3L4_MOUSE (10-312): 1.87e-34: 132: 14.78
+	Hs
		579325 DAPK1_HUMAN (43-515): 3.48e-54: 208: 15.55		ATF6A_HUMAN (4-318): 1.09e-31: 128: 14.03
+	Hs
		402451 PP12C_HUMAN (538-1030): 4.93e-33: 139: 20.35		JUN_HUMAN (48-215): 1.19e-23: 102: 16.47
+	Hs
		257558 ANR17_HUMAN (123-866): 2.56e-17: 89.9: 10.46		FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54
+	Hs
		548317 ANKH1_HUMAN (129-877): 2.32e-16: 86.9: 9.34		FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54
+	Hs
		1219855 ANKH1_HUMAN (129-877): 2.32e-16: 86.9: 9.34		BATF3_HUMAN (120-228): 1.45e-27: 107: 27.52
+	Hs
		257546 ANR17_HUMAN (123-866): 2.56e-17: 89.9: 10.46		JUN_HUMAN (48-215): 1.19e-23: 102: 16.47
+	Hs
		402223 ANKH1_HUMAN (129-877): 2.32e-16: 86.9: 9.34		JUN_HUMAN (48-215): 1.19e-23: 102: 16.47
+	Hs
		92428 E9PDP5_HUMAN (129-881): 7.2e-15: 81.9: 9.96		BATF3_HUMAN (120-228): 1.45e-27: 107: 27.52