HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: JUNB (P17275)
Transcription factor JunB (Transcription factor AP-1 subunit JunB)
Gene: JUNB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1030 Hs			1 347
+	Hs
		161287 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		JUN_HUMAN (1-347): 5.04e-56: 187: 43.89
+	Hs
		402451 PP12C_HUMAN (538-1030): 4.93e-33: 139: 20.35		JUN_HUMAN (1-347): 5.04e-56: 187: 43.89
+	Hs
		257546 ANR17_HUMAN (123-866): 2.56e-17: 89.9: 10.46		JUN_HUMAN (1-347): 5.04e-56: 187: 43.89
+	Hs
		402223 ANKH1_HUMAN (129-877): 2.32e-16: 86.9: 9.34		JUN_HUMAN (1-347): 5.04e-56: 187: 43.89
+	Hs
		257559 ANR17_HUMAN (123-866): 2.56e-17: 89.9: 10.46		CREB1_HUMAN (64-323): 6.09e-26: 107: 14.04
+	Hs
		1219855 ANKH1_HUMAN (129-877): 2.32e-16: 86.9: 9.34		BATF3_HUMAN (242-340): 3.1e-21: 89.8: 26.17
+	Hs
		92428 E9PDP5_HUMAN (129-881): 7.2e-15: 81.9: 9.96		BATF3_HUMAN (242-340): 3.1e-21: 89.8: 26.17