HitPredict

Interactor 1: GAK (O14976)
Cyclin-G-associated kinase (EC 2.7.11.1) (DnaJ homolog subfamily C member 26)
Gene: GAK

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

The method score is based on:

Property	Details
Experiments	24510904, 28514442, 29568061, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016020 - membrane and 5 others more... GO:0016191 - synaptic vesicle uncoating GO:0048471 - perinuclear region of cytoplasm GO:0051085 - chaperone cofactor-dependent protein refolding GO:0051087 - protein-folding chaperone binding GO:0072318 - clathrin coat disassembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	1311
Hs

1	646

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024