HitPredict

Interactor 1: GAK (O14976)
Cyclin-G-associated kinase (EC 2.7.11.1) (DnaJ homolog subfamily C member 26)
Gene: GAK

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.914

The method score is based on:

Property Details
Experiments 24510904, 29513927, 26375402, 24947832
Identification Methods affinity chromatography technology, pull down, protein array, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
and 7 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1311
Hs

1 2527
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024