HitPredict

Interactor 1: GAK (O14976)
Cyclin-G-associated kinase (EC 2.7.11.1) (DnaJ homolog subfamily C member 26)
Gene: GAK

Interactor 2: DAPP1 (Q9UN19)
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa)
Gene: DAPP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1311 Hs			1 280
+	Hs
		433470 SIK2_HUMAN (31-936): 3.13e-171: 535: 15.55		YES_HUMAN (4-280): 3.38e-57: 193: 19.11
+	Hs
		523025 TENS3_HUMAN (402-1221): 5.51e-150: 492: 20.28		SRC_HUMAN (4-280): 1.79e-56: 191: 18.09
+	Hs
		209164 SIK2_HUMAN (31-936): 3.13e-171: 535: 15.55		NCK2_HUMAN (6-129): 4.71e-41: 147: 28.00
+	Hs
		782797 TENS3_HUMAN (402-1221): 5.51e-150: 492: 20.28		CSK_HUMAN (10-280): 6.53e-43: 153: 13.07
+	Hs
		433303 PTEN_HUMAN (396-779): 3.71e-100: 327: 24.14		YES_HUMAN (4-280): 3.38e-57: 193: 19.11
+	Rn
		222449 PTEN_RAT (396-779): 2.15e-100: 327: 24.14		SRC_RAT (4-280): 1.53e-56: 191: 18.09
+	Hs
		789107 PTEN_HUMAN (396-779): 3.71e-100: 327: 24.14		FRK_HUMAN (3-280): 1.52e-53: 183: 18.34
+	Hs
		454830 KCC2B_HUMAN (40-430): 6.64e-91: 310: 22.70		FGR_HUMAN (4-280): 1.36e-55: 189: 17.41
+	Rn
		222445 PTEN_RAT (396-779): 2.15e-100: 327: 24.14		CSK_RAT (10-280): 2.05e-45: 160: 15.14
+	Hs
		890847 PTEN_HUMAN (396-779): 3.71e-100: 327: 24.14		PKHA1_HUMAN (128-254): 1.44e-34: 130: 31.11
+	Hs
		337569 BMP2K_HUMAN (35-311): 2.28e-41: 168: 41.79		ABL1_HUMAN (8-280): 6.5e-51: 181: 17.61
+	Hs
		69213 BMP2K_HUMAN (35-311): 2.28e-41: 168: 41.79		A9UF07_HUMAN (8-280): 3.03e-49: 176: 17.61
+	Hs
		433843 TPTE2_HUMAN (407-558): 8.86e-30: 127: 39.75		LYN_HUMAN (3-280): 2.64e-55: 187: 18.37
+	Ce
		105413 SEL5_CAEEL (30-333): 2.44e-36: 152: 37.54		Q95PW9_CAEEL (10-131): 2.68e-43: 153: 33.61
+	Hs
		274188 STK16_HUMAN (46-316): 3.31e-29: 121: 30.50		CSK_HUMAN (10-280): 6.53e-43: 153: 13.07
+	Hs
		986017 NEK1_HUMAN (37-312): 1.71e-26: 120: 31.94		PTN11_HUMAN (35-225): 1.69e-29: 118: 22.28
+	Hs
		782828 TENS1_HUMAN (544-1199): 1.23e-13: 78.4: 12.33		CSK_HUMAN (10-280): 6.53e-43: 153: 13.07
+	Hs
		782795 TENS2_HUMAN (756-1199): 2.65e-09: 64.1: 14.44		CSK_HUMAN (10-280): 6.53e-43: 153: 13.07