HitPredict

Interactor 1: AZIN1 (O14977)
Antizyme inhibitor 1 (AZI) (AZI1) (Ornithine decarboxylase antizyme inhibitor)
Gene: AZIN1

Interactor 2: OAZ1 (P54368)
Ornithine decarboxylase antizyme 1 (AZ1) (ODC-Az)
Gene: OAZ1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.929

Property	Details
Experiments	18062773, 26496610, 26186194, 28514442, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	ODC_AZ~Orn_Arg_deC_N, ODC_AZ~Orn_DAP_Arg_deC
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 448 Hs			1 228
+	Hs
		516205 DCOR_HUMAN (1-446): 0: 573: 49.56		OAZ1_HUMAN (1-218): 1.98e-124: 353: 100.00
+	Mm
		870316 AZIN2_MOUSE (1-438): 1.31e-172: 493: 42.73		OAZ1_MOUSE (1-227): 4.74e-138: 387: 84.14
+	Hs
		870311 AZIN2_HUMAN (1-438): 0: 516: 43.85		OAZ1_HUMAN (1-218): 1.98e-124: 353: 100.00
+	Hs
		306924 DCOR_HUMAN (1-446): 0: 573: 49.56		OAZ2_HUMAN (54-226): 7.65e-83: 246: 55.17
+	Hs
		516220 DCOR_HUMAN (1-446): 0: 573: 49.56		OAZ3_HUMAN (64-221): 6.85e-74: 225: 36.25
+	Hs
		161750 AZIN1_HUMAN (1-448): 0: 535: 100.00		OAZ2_HUMAN (54-226): 7.65e-83: 246: 55.17
+	Hs
		306928 AZIN2_HUMAN (1-438): 0: 516: 43.85		OAZ2_HUMAN (54-226): 7.65e-83: 246: 55.17
+	Hs
		161763 AZIN1_HUMAN (1-448): 0: 535: 100.00		OAZ3_HUMAN (64-221): 6.85e-74: 225: 36.25
+	Hs
		1283666 AZIN2_HUMAN (1-438): 0: 516: 43.85		OAZ3_HUMAN (64-221): 6.85e-74: 225: 36.25
+	Mm
		139601 AZIN2_MOUSE (1-438): 1.31e-172: 493: 42.73		OAZ2_MOUSE (54-226): 7.65e-83: 246: 55.17
+	Mm
		1207363 AZIN2_MOUSE (1-438): 1.31e-172: 493: 42.73		OAZ3_MOUSE (69-222): 1.44e-73: 224: 34.62