HitPredict

Interactor 1: ZN263 (O14978)
Zinc finger protein 263 (Zinc finger protein FPM315) (Zinc finger protein with KRAB and SCAN domains 12)
Gene: ZNF263

Interactor 2: ZN446 (Q9NWS9)
Zinc finger protein 446 (Zinc finger protein with KRAB and SCAN domains 20)
Gene: ZNF446

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.875

The method score is based on:

Property Details
Experiments 16189514, 28514442, 33961781
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SCAN~SCAN, zf-C2H2~zf-C2H2
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0046872 - metal ion binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 683
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024