HitPredict

Interactor 1: HNRDL (O14979)
Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1)
Gene: HNRNPDL

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24189400
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 420 Hs			1 654
+	Hs
		453103 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		503724 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		453102 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		501856 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		453234 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		HSP72_HUMAN (25-636): 0: 905: 64.51
+	Hs
		609729 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		HS71L_HUMAN (24-647): 0: 922: 63.16
+	Hs
		609901 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		Q53FA3_HUMAN (24-647): 0: 922: 63.00
+	Hs
		503440 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		501680 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		483748 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		HS71A_HUMAN (26-635): 0: 911: 64.11
+	Hs
		504019 PABP4_HUMAN (61-335): 1.63e-59: 206: 17.87		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		504060 HNRPD_HUMAN (111-420): 3.55e-62: 206: 56.45		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		564075 HNRPD_HUMAN (111-420): 3.55e-62: 206: 56.45		HSP76_HUMAN (25-635): 0: 915: 62.54
+	Hs
		502053 PABP4_HUMAN (61-335): 1.63e-59: 206: 17.87		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		502086 HNRPD_HUMAN (111-420): 3.55e-62: 206: 56.45		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		502169 RA1L2_HUMAN (136-420): 1.11e-54: 185: 33.68		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		502470 ROAA_HUMAN (19-233): 6.29e-24: 103: 18.81		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		503332 PABP1_HUMAN (223-321): 4.94e-14: 76.1: 20.00		HSP7C_HUMAN (26-637): 0: 916: 66.02