HitPredict

Interactor 1: HNRDL (O14979)
Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1)
Gene: HNRNPDL

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0006396 - RNA processing GO:0008143 - poly(A) binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 420 Hs			1 644
+	Hs
		453331 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		161948 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		453107 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516424 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516358 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516495 PABP4_HUMAN (61-335): 1.63e-59: 206: 17.87		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516511 HNRPD_HUMAN (111-420): 3.55e-62: 206: 56.45		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516663 ROAA_HUMAN (19-233): 6.29e-24: 103: 18.81		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Dm
		597049 RB27C_DROME (143-407): 8.49e-78: 248: 29.49		PABP_DROME (2-464): 6.23e-64: 224: 22.09
+	Dm
		597051 SQD_DROME (114-315): 4.84e-53: 182: 37.13		PABP_DROME (2-464): 6.23e-64: 224: 22.09
+	Hs
		609862 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15
+	Sc
		376562 PABP_YEAST (115-327): 6.49e-38: 146: 16.59		PABP_YEAST (2-290): 4.28e-66: 228: 30.07
+	Hs
		453138 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		474021 PABP4_HUMAN (61-335): 1.63e-59: 206: 17.87		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		453526 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		852134 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		582288 HNRPD_HUMAN (111-420): 3.55e-62: 206: 56.45		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		1119141 PAP1L_HUMAN (58-335): 3.92e-60: 207: 16.33		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		680450 HNRPD_HUMAN (111-420): 3.55e-62: 206: 56.45		TIA1_HUMAN (4-109): 7.62e-12: 69.5: 24.53
+	Zm
		8143 A0A1D6ELH4_MAIZE (37-315): 1.6e-49: 179: 19.45		A0A1D6ELH4_MAIZE (1-89): 1.11e-15: 82.6: 30.34