HitPredict

Interactor 1: HNRDL (O14979)
Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1)
Gene: HNRNPDL

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0010468 - regulation of gene expression
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 420 Hs			1 577
+	Hs
		128000 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		128079 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		453668 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		852190 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		128025 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		610081 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		453375 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43
+	Hs
		453739 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		852215 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		453542 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		453522 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		852129 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		453516 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		610131 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		610004 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		453374 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		852064 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		609990 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		609880 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Dm
		112938 RB27C_DROME (143-407): 8.49e-78: 248: 29.49		M9NF14_DROME (460-571): 2.3e-09: 62.3: 20.18