HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.726

Property	Details
Experiments	26673895, 29467282, 32140074, 35013218, 36424410, 17314511
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0032991 - protein-containing complex
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 454
+	Hs
		162327 XPO1_HUMAN (1-1071): 0: 1022: 100.00		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		163302 XPO1_HUMAN (1-1071): 0: 1022: 100.00		MLXIP_HUMAN (9-446): 1.64e-52: 191: 13.83
+	Hs
		162255 XPO1_HUMAN (1-1071): 0: 1022: 100.00		MITF_HUMAN (155-450): 1.47e-29: 123: 14.47
+	Hs
		162396 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TFEB_HUMAN (180-450): 2.56e-28: 118: 14.59
+	Hs
		162570 XPO1_HUMAN (1-1071): 0: 1022: 100.00		MAX_HUMAN (354-454): 1.39e-24: 101: 32.67
+	Hs
		297143 IPO13_HUMAN (17-1029): 3.79e-133: 429: 16.03		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347506 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		207869 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		348174 XPO7_HUMAN (23-1013): 1.48e-120: 398: 13.18		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347933 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346809 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		348361 TNPO3_HUMAN (24-901): 9.93e-89: 307: 14.37		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		1016065 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54