HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	26673895, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 648
+	Xl
		1155625 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6PA51_XENLA (4-646): 6.32e-175: 514: 57.60
+	Hs
		162361 XPO1_HUMAN (1-1071): 0: 1022: 100.00		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		162956 XPO1_HUMAN (1-1071): 0: 1022: 100.00		KSR1_HUMAN (138-648): 6.15e-108: 348: 24.61
+	Hs
		374247 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		207878 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		488718 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28