HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~Xpo1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 225
+	Hs
		162352 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56
+	Xl
		1151598 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6GQE6_XENLA (1-225): 1.8e-48: 160: 80.00
+	Xl
		1155699 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q7ZXI5_XENLA (2-225): 9.25e-42: 144: 45.32
+	Hs
		162812 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PAP1L_HUMAN (8-151): 9.06e-19: 86.3: 13.79
+	Hs
		162702 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PABP4_HUMAN (148-225): 1.72e-13: 70.9: 19.28
+	Hs
		162372 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PABP1_HUMAN (141-225): 2.1e-13: 70.5: 17.78
+	Hs
		162310 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PTBP3_HUMAN (4-224): 2.96e-13: 70.1: 15.35
+	Hs
		162636 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TIAR_HUMAN (143-223): 1.61e-10: 61.7: 26.19
+	Sc
		676283 XPO1_YEAST (14-1067): 0: 848: 46.08		NAM8_YEAST (1-224): 5.12e-42: 150: 16.09
+	Hs
		321155 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		PTBP3_HUMAN (4-224): 2.96e-13: 70.1: 15.35
+	Hs
		155505 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		PTBP3_HUMAN (4-224): 2.96e-13: 70.1: 15.35
+	Hs
		321210 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		PTBP3_HUMAN (4-224): 2.96e-13: 70.1: 15.35