HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36585612
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 215
+	Hs
		162668 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50
+	Hs
		162498 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91
+	Hs
		163397 XPO1_HUMAN (1-1071): 0: 1022: 100.00		HM20B_HUMAN (64-165): 1.22e-15: 76: 32.35
+	Xl
		1001500 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q0IH27_XENLA (54-165): 1.1e-17: 81.3: 30.36
+	Xl
		639845 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		UBF1A_XENLA (4-209): 8.2e-09: 56.6: 16.07
+	Sc
		675927 XPO1_YEAST (14-1067): 0: 848: 46.08		IXR1_YEAST (79-174): 6.78e-16: 77.4: 23.96
+	Hs
		818325 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91
+	Mm
		996628 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		SSRP1_MOUSE (2-86): 8.41e-10: 59.8: 31.77
+	Mm
		639842 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		UBF1_MOUSE (49-203): 2.84e-09: 58.2: 20.25
+	Hs
		818480 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91
+	Ce
		136638 O62332_CAEEL (24-1051): 7.76e-104: 348: 12.93		SSP1B_CAEEL (91-208): 5.6e-18: 83.7: 32.80
+	Hs
		818663 TNPO3_HUMAN (24-901): 9.93e-89: 307: 14.37		SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91
+	Hs
		1060882 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		CIC_HUMAN (3-96): 2.76e-12: 67: 22.34