HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 758
+	Dm
		1353152 XPO1_DROME (4-1071): 0: 905: 70.72		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96
+	Hs
		497394 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		155519 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497757 XPO7_HUMAN (23-1013): 1.48e-120: 398: 13.18		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497032 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		581954 IMB1_RAT (27-908): 1.81e-90: 311: 11.44		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94177 IMB1_RAT (27-908): 1.81e-90: 311: 11.44		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		497465 XPO6_HUMAN (20-380): 2.55e-64: 239: 16.71		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		1112953 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		FHDC1_MOUSE (6-674): 5.03e-33: 139: 14.92
+	Hs
		1056831 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57