HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.629

Property	Details
Experiments	11932251, 35271311
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0031267 - small GTPase binding GO:0032991 - protein-containing complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 421
+	Hs
		162308 XPO1_HUMAN (1-1071): 0: 1022: 100.00		HERC2_HUMAN (15-182): 2.22e-22: 102: 19.88
+	Hs
		163037 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NEK9_HUMAN (32-278): 1.27e-09: 62.4: 26.04
+	Sc
		601743 XPO1_YEAST (14-1067): 0: 848: 46.08		RCC1_YEAST (192-419): 1.22e-30: 124: 18.85
+	Hs
		578435 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Mm
		1225127 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		NEK9_MOUSE (32-278): 1.98e-09: 61.6: 26.04