HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	23825024, 35271311
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol and 1 others more... GO:0031965 - nuclear membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 101
+	Hs
		162574 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		162553 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42
+	Mm
		928249 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		SUMO1_MOUSE (1-101): 1.01e-41: 134: 100.00
+	Rn
		88681 D3ZQE8_RAT (26-665): 1.44e-104: 357: 19.02		SUMO3_RAT (1-100): 1.5e-39: 128: 46.00
+	Hs
		902759 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		928098 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00