HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: FOXO4 (P98177)
Forkhead box protein O4 (Fork head domain transcription factor AFX1)
Gene: FOXO4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	11313479
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 505
+	Hs
		162226 XPO1_HUMAN (1-1071): 0: 1022: 100.00		FOXO3_HUMAN (46-502): 3.73e-64: 222: 35.35
+	Hs
		162678 XPO1_HUMAN (1-1071): 0: 1022: 100.00		FOXO1_HUMAN (23-502): 1.08e-55: 199: 34.59
+	Hs
		162551 XPO1_HUMAN (1-1071): 0: 1022: 100.00		FOXA1_HUMAN (4-410): 8.56e-47: 171: 19.86
+	Hs
		162639 XPO1_HUMAN (1-1071): 0: 1022: 100.00		FOXK2_HUMAN (33-459): 3.11e-45: 170: 18.39
+	Hs
		162628 XPO1_HUMAN (1-1071): 0: 1022: 100.00		FOXK1_HUMAN (5-443): 4.01e-43: 164: 19.39
+	Hs
		1169835 XPO7_HUMAN (23-1013): 1.48e-120: 398: 13.18		FOXI2_HUMAN (2-325): 1.1e-45: 164: 24.23
+	Ce
		184216 O62332_CAEEL (24-1051): 7.76e-104: 348: 12.93		FOXO_CAEEL (22-502): 7.96e-61: 210: 25.00
+	Hs
		206839 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		FOXO3_HUMAN (46-502): 3.73e-64: 222: 35.35
+	Hs
		877901 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		FOXA1_HUMAN (4-410): 8.56e-47: 171: 19.86