HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: NFKB2 (Q00653)
Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit]
Gene: NFKB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 900
+	Xl
		251120 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		NFKB2_XENLA (5-879): 0: 607: 49.95
+	Hs
		162399 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NFKB1_HUMAN (6-881): 0: 586: 41.27
+	Hs
		162654 XPO1_HUMAN (1-1071): 0: 1022: 100.00		REL_HUMAN (33-456): 2.67e-112: 359: 33.88
+	Hs
		162653 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TF65_HUMAN (24-354): 9.91e-113: 358: 40.96
+	Hs
		162640 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RELB_HUMAN (27-356): 5.22e-89: 296: 39.34
+	Hs
		163457 XPO1_HUMAN (1-1071): 0: 1022: 100.00		ANR50_HUMAN (290-733): 3.41e-77: 277: 15.72
+	Hs
		163008 XPO1_HUMAN (1-1071): 0: 1022: 100.00		ANR52_HUMAN (285-599): 1.64e-32: 138: 18.58
+	Hs
		121547 XPO1_HUMAN (1-1071): 0: 1022: 100.00		IKBE_HUMAN (472-704): 4.58e-25: 112: 38.98
+	Hs
		162298 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TNKS1_HUMAN (638-899): 2.21e-24: 112: 18.27
+	Hs
		162419 XPO1_HUMAN (1-1071): 0: 1022: 100.00		IKBA_HUMAN (486-677): 9.26e-26: 110: 39.38
+	Xl
		1117304 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q4KLR5_XENLA (477-704): 1.13e-28: 120: 39.47
+	Xl
		1150110 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6DCW3_XENLA (485-677): 1.64e-27: 115: 35.71
+	Hs
		162776 XPO1_HUMAN (1-1071): 0: 1022: 100.00		IKBB_HUMAN (486-692): 3.79e-20: 95.1: 33.74
+	Mm
		1119759 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		ANR28_MOUSE (266-780): 1.18e-76: 272: 15.85
+	Hs
		978756 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		TF65_HUMAN (24-354): 9.91e-113: 358: 40.96
+	Hs
		964483 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		RELB_HUMAN (27-356): 5.22e-89: 296: 39.34
+	Mm
		71300 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		ANR44_MOUSE (271-527): 3.21e-19: 95.4: 10.67
+	Hs
		1206059 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		MIB1_HUMAN (564-805): 4.43e-30: 130: 20.54