HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 768
+	Hs
		162720 XPO1_HUMAN (1-1071): 0: 1022: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1042209 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		155572 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		207935 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042786 XPO7_HUMAN (23-1013): 1.48e-120: 398: 13.18		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042573 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041594 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042938 TNPO3_HUMAN (24-901): 9.93e-89: 307: 14.37		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Mm
		1111820 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		CUL4A_MOUSE (5-768): 0: 796: 37.68
+	Hs
		1042989 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043355 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		207975 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		CUL5_HUMAN (25-768): 0: 597: 23.77