HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: NUP54 (Q7Z3B4)
Nucleoporin p54 (54 kDa nucleoporin)
Gene: NUP54

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 37516964
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0006913 - nucleocytoplasmic transport GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1071 Hs			1 507
+	Hs
		162244 XPO1_HUMAN (1-1071): 0: 1022: 100.00		GANP_HUMAN (3-277): 2.29e-18: 91.2: 12.16
+	Hs
		162448 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Hs
		162534 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NUP98_HUMAN (2-257): 4.92e-12: 70.8: 15.44
+	Sc
		676198 XPO1_YEAST (14-1067): 0: 848: 46.08		NU145_YEAST (2-422): 1.95e-69: 243: 15.68
+	Hs
		162539 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SC24C_HUMAN (8-332): 8.74e-10: 63.5: 9.76
+	Sc
		676195 XPO1_YEAST (14-1067): 0: 848: 46.08		NUP57_YEAST (3-489): 1.88e-59: 206: 18.52
+	Sc
		676301 XPO1_YEAST (14-1067): 0: 848: 46.08		NU116_YEAST (5-265): 1.36e-12: 72.3: 13.51
+	Sc
		676294 XPO1_YEAST (14-1067): 0: 848: 46.08		NUP49_YEAST (6-267): 5.59e-11: 66.6: 11.28
+	Sc
		676117 XPO1_YEAST (14-1067): 0: 848: 46.08		NU159_YEAST (44-283): 8.5e-10: 63.5: 10.36
+	Tt
		101847 G0RZB7_CHATD (22-1068): 0: 819: 48.14		NU145_CHATD (13-289): 8.68e-13: 73.1: 12.59
+	Sc
		830686 MTR10_YEAST (37-715): 9.12e-91: 314: 14.95		NU145_YEAST (2-422): 1.95e-69: 243: 15.68
+	Sc
		823014 MTR10_YEAST (37-715): 9.12e-91: 314: 14.95		NUP57_YEAST (3-489): 1.88e-59: 206: 18.52
+	Hs
		727300 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Hs
		858024 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		NUP98_HUMAN (2-257): 4.92e-12: 70.8: 15.44
+	Hs
		155553 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		NUP98_HUMAN (2-257): 4.92e-12: 70.8: 15.44
+	Hs
		727318 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Ce
		248186 O62332_CAEEL (24-1051): 7.76e-104: 348: 12.93		Q9XWK3_CAEEL (11-206): 2.02e-12: 71.6: 19.62
+	Ce
		248185 O62332_CAEEL (24-1051): 7.76e-104: 348: 12.93		Q9U3B9_CAEEL (3-223): 1.41e-11: 68.9: 13.00
+	Ce
		248176 O62332_CAEEL (24-1051): 7.76e-104: 348: 12.93		Q21295_CAEEL (8-208): 8.74e-09: 60: 12.20
+	Sc
		774386 MTR10_YEAST (37-715): 9.12e-91: 314: 14.95		NU159_YEAST (44-283): 8.5e-10: 63.5: 10.36