HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: NUP50 (Q9UKX7)
Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50)
Gene: NUP50

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37516964
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CRM1_C~Ran_BP1
Common GO terms	GO:0005635 - nuclear envelope GO:0005654 - nucleoplasm GO:0006913 - nucleocytoplasmic transport GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1071 Hs			1 468
+	Hs
		152753 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RGPD8_HUMAN (196-468): 2.51e-39: 154: 14.34
+	Hs
		63864 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RGPD3_HUMAN (196-468): 4.76e-39: 153: 14.69
+	Hs
		162481 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38
+	Hs
		162518 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RBP2_HUMAN (212-468): 1.6e-36: 146: 17.60
+	Sc
		676138 XPO1_YEAST (14-1067): 0: 848: 46.08		YRB1_YEAST (295-467): 3.08e-34: 129: 21.23
+	Sc
		676121 XPO1_YEAST (14-1067): 0: 848: 46.08		YRB2_YEAST (182-467): 2.35e-31: 124: 15.67
+	Hs
		297205 IPO13_HUMAN (17-1029): 3.79e-133: 429: 16.03		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Hs
		1273239 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Xl
		1137361 Q5U4V0_XENLA (33-1045): 8.68e-130: 418: 13.75		Q6DCU3_XENLA (1-467): 1.98e-108: 330: 56.10
+	Hs
		1334950 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Hs
		1273208 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		RGPD5_HUMAN (196-468): 4.34e-39: 153: 14.34
+	Hs
		297160 IPO13_HUMAN (17-1029): 3.79e-133: 429: 16.03		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38
+	Hs
		796783 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38
+	Hs
		834809 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		RBP2_HUMAN (212-468): 1.6e-36: 146: 17.60
+	Hs
		155547 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38
+	Mm
		1322246 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		RBP2_MOUSE (209-468): 3.15e-38: 151: 16.79
+	Hs
		796812 XPO7_HUMAN (23-1013): 1.48e-120: 398: 13.18		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38
+	Hs
		483396 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		RGPD1_HUMAN (212-468): 1.43e-40: 157: 17.23
+	Hs
		152779 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		RGPD8_HUMAN (196-468): 2.51e-39: 154: 14.34
+	Hs
		796746 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38