HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:1990904 - ribonucleoprotein complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 456
+	Xl
		1151740 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6GR29_XENLA (1-456): 0: 702: 95.61
+	Hs
		163485 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Xl
		1001504 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q0IH85_XENLA (2-455): 0: 660: 44.96
+	Mm
		888120 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		RUVB1_MOUSE (1-456): 0: 704: 99.78
+	Hs
		1060972 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		1060971 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		RUVB2_HUMAN (2-455): 0: 651: 42.76