HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: AP4B1 (Q9Y6B7)
AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin)
Gene: AP4B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 739
+	Hs
		162606 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP2B1_HUMAN (3-611): 0: 576: 28.53
+	Hs
		162675 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1B1_HUMAN (3-614): 0: 567: 29.03
+	Xl
		1155726 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q7ZYG7_XENLA (3-611): 0: 572: 28.69
+	Xl
		50503 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		A1L2H5_XENLA (3-624): 0: 558: 27.78
+	Hs
		162233 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1G1_HUMAN (6-614): 1.44e-164: 496: 13.96
+	Xl
		1151538 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6GPE1_XENLA (6-623): 3.2e-162: 490: 13.96
+	Hs
		119888 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP3B1_HUMAN (4-587): 3.69e-151: 470: 21.68
+	Hs
		162272 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1G2_HUMAN (5-599): 8.7e-152: 462: 15.05
+	Hs
		162312 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP2A1_HUMAN (5-594): 1.08e-147: 457: 14.88
+	Xl
		1119807 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q52KY5_XENLA (4-589): 2.84e-150: 467: 22.01
+	Sc
		647437 XPO1_YEAST (14-1067): 0: 848: 46.08		AP2B_YEAST (20-630): 2.67e-149: 453: 21.96
+	Hs
		163409 XPO1_HUMAN (1-1071): 0: 1022: 100.00		COPG2_HUMAN (28-523): 1.21e-76: 266: 18.80
+	Hs
		163533 XPO1_HUMAN (1-1071): 0: 1022: 100.00		COPG1_HUMAN (31-522): 2.07e-75: 263: 17.00
+	Sc
		675950 XPO1_YEAST (14-1067): 0: 848: 46.08		AP1B1_YEAST (2-579): 6.48e-142: 435: 26.47
+	Xl
		1155621 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6P7I2_XENLA (31-554): 1.73e-74: 260: 16.94
+	Xl
		1150313 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		COPG2_XENLA (28-522): 4.07e-74: 259: 18.25
+	Sc
		676161 XPO1_YEAST (14-1067): 0: 848: 46.08		AP3B_YEAST (11-538): 7.65e-108: 348: 20.36
+	Mm
		1321796 XPOT_MOUSE (29-1023): 6.32e-125: 407: 14.83		AP3B1_MOUSE (3-587): 3.33e-140: 441: 21.92