HitPredict

Interactor 1: BTAF1 (O14981)
TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172)
Gene: BTAF1

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1849 Hs			1 454
+	Hs
		348113 CHD7_HUMAN (1067-1837): 0: 669: 21.89		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347951 CHD8_HUMAN (1067-1837): 0: 647: 21.78		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346938 CHD9_HUMAN (1070-1837): 0: 639: 22.22		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		151469 CHD2_HUMAN (1101-1849): 0: 634: 23.34		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346268 SMCA4_HUMAN (1189-1843): 0: 633: 24.93		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346805 CHD4_HUMAN (1109-1849): 0: 629: 20.79		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347406 CHD5_HUMAN (1090-1809): 0: 629: 20.61		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		229271 SMCA5_HUMAN (1165-1848): 0: 625: 25.46		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Mm
		348422 SMCA4_MOUSE (1189-1843): 0: 632: 26.02		MYC_MOUSE (1-454): 4.33e-119: 357: 89.01
+	Mm
		348432 CHD4_MOUSE (1109-1849): 0: 630: 20.79		MYC_MOUSE (1-454): 4.33e-119: 357: 89.01
+	Hs
		379973 CHD7_HUMAN (1067-1837): 0: 669: 21.89		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		151473 CHD2_HUMAN (1101-1849): 0: 634: 23.34		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379142 SMCA4_HUMAN (1189-1843): 0: 633: 24.93		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379411 CHD4_HUMAN (1109-1849): 0: 629: 20.79		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		229276 SMCA5_HUMAN (1165-1848): 0: 625: 25.46		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		607839 CHD8_HUMAN (1067-1837): 0: 647: 21.78		USF1_HUMAN (175-453): 1.02e-39: 146: 18.40
+	Mm
		1111973 SMCA4_MOUSE (1189-1843): 0: 632: 26.02		SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61
+	Hs
		229308 SMCA5_HUMAN (1165-1848): 0: 625: 25.46		USF1_HUMAN (175-453): 1.02e-39: 146: 18.40
+	Hs
		738948 SMCA4_HUMAN (1189-1843): 0: 633: 24.93		SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19
+	Dm
		631342 BRM_DROME (1098-1842): 0: 631: 24.78		MYC_DROME (210-454): 3.25e-30: 126: 26.74