HitPredict

Interactor 1: BTAF1 (O14981)
TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172)
Gene: BTAF1

Interactor 2: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	9488487, 35271311, 9159119
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1849 Hs			1 339
+	Dm
		589973 Q9VF02_DROME (4-1849): 0: 1990: 45.16		TBP_DROME (11-339): 2.81e-105: 314: 54.37
+	Sc
		526962 BTAF1_YEAST (3-1849): 0: 1808: 36.06		TBP_YEAST (120-337): 9.51e-102: 301: 69.73
+	Mm
		661500 SMCA4_MOUSE (1189-1843): 0: 632: 26.02		TBP_MOUSE (1-339): 8.88e-142: 405: 91.15
+	Hs
		589810 SMCA2_HUMAN (1216-1842): 0: 595: 26.25		TBP_HUMAN (1-339): 7.86e-144: 411: 100.00
+	Sc
		526973 STH1_YEAST (1194-1839): 6.83e-175: 570: 27.53		TBP_YEAST (120-337): 9.51e-102: 301: 69.73
+	Dm
		1097626 ISWI_DROME (1259-1848): 0: 590: 27.81		Q8T052_DROME (128-338): 2.89e-78: 253: 37.56