HitPredict

Interactor 1: BTAF1 (O14981)
TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172)
Gene: BTAF1

Interactor 2: FOXL2 (P58012)
Forkhead box protein L2
Gene: FOXL2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1849 Hs			1 376
+	Hs
		163590 BTAF1_HUMAN (1-1849): 0: 2427: 100.00		FOXG1_HUMAN (11-334): 5.9e-50: 176: 27.80
+	Hs
		163600 BTAF1_HUMAN (1-1849): 0: 2427: 100.00		FOXL1_HUMAN (28-215): 7.39e-48: 167: 45.21
+	Hs
		163640 BTAF1_HUMAN (1-1849): 0: 2427: 100.00		FOXB1_HUMAN (43-352): 7.6e-43: 153: 27.01
+	Hs
		163614 BTAF1_HUMAN (1-1849): 0: 2427: 100.00		FOXI2_HUMAN (54-143): 5.64e-24: 102: 65.56
+	Hs
		126411 BTAF1_HUMAN (1-1849): 0: 2427: 100.00		FOXE1_HUMAN (54-142): 1.43e-21: 96.7: 67.42
+	Hs
		1021365 CHD7_HUMAN (1067-1837): 0: 669: 21.89		FOXL1_HUMAN (28-215): 7.39e-48: 167: 45.21
+	Hs
		877716 CHD3_HUMAN (1110-1849): 0: 656: 19.63		FOXA1_HUMAN (10-340): 9.06e-47: 167: 26.55
+	Hs
		877612 CHD4_HUMAN (1109-1849): 0: 629: 20.79		FOXG1_HUMAN (11-334): 5.9e-50: 176: 27.80
+	Hs
		229346 SMCA5_HUMAN (1165-1848): 0: 625: 25.46		FOXG1_HUMAN (11-334): 5.9e-50: 176: 27.80
+	Dm
		631310 BRM_DROME (1098-1842): 0: 631: 24.78		FOXO_DROME (6-266): 2.02e-45: 166: 23.79
+	Hs
		877733 CHD4_HUMAN (1109-1849): 0: 629: 20.79		FOXA1_HUMAN (10-340): 9.06e-47: 167: 26.55
+	Dm
		1279980 Q9VPL9_DROME (1109-1837): 0: 626: 21.37		FOXO_DROME (6-266): 2.02e-45: 166: 23.79
+	Hs
		846951 SMCA4_HUMAN (1189-1843): 0: 633: 24.93		FOXC1_HUMAN (14-227): 2.8e-43: 159: 36.70
+	Hs
		964181 CHD4_HUMAN (1109-1849): 0: 629: 20.79		FOXK2_HUMAN (3-333): 6.42e-44: 162: 24.10
+	Mm
		725295 SMCA4_MOUSE (1189-1843): 0: 632: 26.02		FOXA2_MOUSE (1-330): 1.71e-43: 158: 23.28
+	Hs
		1021109 CHD4_HUMAN (1109-1849): 0: 629: 20.79		FOXC1_HUMAN (14-227): 2.8e-43: 159: 36.70
+	Hs
		208877 SMCA5_HUMAN (1165-1848): 0: 625: 25.46		FOXS1_HUMAN (43-324): 1.74e-44: 158: 34.50
+	Hs
		126446 SMCA4_HUMAN (1189-1843): 0: 633: 24.93		FOXE1_HUMAN (54-142): 1.43e-21: 96.7: 67.42
+	Hs
		126461 CHD4_HUMAN (1109-1849): 0: 629: 20.79		FOXE1_HUMAN (54-142): 1.43e-21: 96.7: 67.42
+	Hs
		126415 SMCA5_HUMAN (1165-1848): 0: 625: 25.46		FOXE1_HUMAN (54-142): 1.43e-21: 96.7: 67.42