HitPredict

Interactor 1: BTAF1 (O14981)
TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172)
Gene: BTAF1

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~SNF2-rel_dom
Common GO terms	GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1849 Hs			1 183
+	Hs
		1027300 CHD7_HUMAN (1067-1837): 0: 669: 21.89		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1018451 CHD3_HUMAN (1110-1849): 0: 656: 19.63		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027277 CHD8_HUMAN (1067-1837): 0: 647: 21.78		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027026 CHD9_HUMAN (1070-1837): 0: 639: 22.22		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		846954 SMCA4_HUMAN (1189-1843): 0: 633: 24.93		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Mm
		1161080 CHD4_MOUSE (1109-1849): 0: 630: 20.79		Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027001 CHD4_HUMAN (1109-1849): 0: 629: 20.79		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027145 CHD5_HUMAN (1090-1809): 0: 629: 20.61		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		229384 SMCA5_HUMAN (1165-1848): 0: 625: 25.46		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800360 CHD3_HUMAN (1110-1849): 0: 656: 19.63		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949764 CHD3_HUMAN (1110-1849): 0: 656: 19.63		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		800320 SMCA4_HUMAN (1189-1843): 0: 633: 24.93		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		800380 CHD4_HUMAN (1109-1849): 0: 629: 20.79		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		846923 SMCA4_HUMAN (1189-1843): 0: 633: 24.93		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Mm
		949943 CHD4_MOUSE (1109-1849): 0: 630: 20.79		CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33
+	Hs
		949784 CHD4_HUMAN (1109-1849): 0: 629: 20.79		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		123332 CHD7_HUMAN (1067-1837): 0: 669: 21.89		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		203687 CHD4_HUMAN (1109-1849): 0: 629: 20.79		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20
+	Hs
		123245 CHD3_HUMAN (1110-1849): 0: 656: 19.63		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		847118 SMCA4_HUMAN (1189-1843): 0: 633: 24.93		CDYL_HUMAN (16-165): 6.53e-34: 127: 25.16