Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: ZWINT (O95229)
Outer kinetochore KNL1 complex subunit ZWINT (ZW10 interactor) (ZW10-interacting protein 1) (Zwint-1)
Gene: ZWINT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.55 0.724

The method score is based on:

Property Details
Experiments 34079125, 26186194, 26496610, 28514442, 33961781, 20360068, 15824131, 16732327, 25416956, unassigned3799
Identification Methods proximity labelling technology, affinity chromatography technology, tandem affinity purification, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid, mammalian protein protein interaction trap
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000070 - mitotic sister chromatid segregation
GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025