Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: SPC24 (Q8NBT2)
Kinetochore protein Spc24 (hSpc24)
Gene: SPC24

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 26186194, 26496610, 28514442, 24981860, 33961781, 14699129, 20360068, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DUF5595~Spc24
Common GO terms GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007059 - chromosome segregation
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 642
Hs

1 197
+ Xl

Service provided by Combinatics, Japan

Last updated: 11Aug2025