HitPredict

Interactor 1: AT2A1 (O14983)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A1

Interactor 2: ITM2B (Q9Y287)
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]
Gene: ITM2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 266
+	Rn
		1140241 AT2A1_RAT (1-994): 0: 973: 96.78		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24
+	Rn
		513727 AT2A2_RAT (1-1000): 0: 951: 83.50		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24
+	Rn
		416154 AT1A1_RAT (2-998): 0: 805: 26.49		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24
+	Rn
		416173 AT1A3_RAT (2-998): 0: 798: 26.20		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24
+	Hs
		531005 AT1A3_HUMAN (2-998): 0: 800: 26.20		ITM2B_HUMAN (1-266): 1.45e-148: 417: 100.00
+	Rn
		416165 AT1A2_RAT (2-998): 0: 789: 26.58		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24
+	Hs
		619300 AT2B4_HUMAN (5-993): 0: 761: 25.05		ITM2B_HUMAN (1-266): 1.45e-148: 417: 100.00
+	Rn
		1140240 AT2B3_RAT (3-993): 0: 753: 24.22		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24