HitPredict

Interactor 1: ARHGA (O15013)
Rho guanine nucleotide exchange factor 10
Gene: ARHGEF10

Interactor 2: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1369 Hs			1 1106
+	Hs
		164125 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58
+	Hs
		164095 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		164101 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73
+	Hs
		452448 FGD6_HUMAN (93-924): 2.64e-89: 320: 12.65		PGFRB_HUMAN (1-1106): 0: 795: 100.00
+	Hs
		452375 VAV2_HUMAN (302-922): 4.52e-91: 317: 16.39		PGFRB_HUMAN (1-1106): 0: 795: 100.00
+	Hs
		452342 VAV_HUMAN (297-904): 1.46e-90: 315: 15.35		PGFRB_HUMAN (1-1106): 0: 795: 100.00
+	Hs
		452499 FARP1_HUMAN (239-836): 7.11e-76: 276: 13.99		PGFRB_HUMAN (1-1106): 0: 795: 100.00
+	Hs
		452495 VAV3_HUMAN (357-696): 3.83e-76: 273: 21.33		PGFRB_HUMAN (1-1106): 0: 795: 100.00
+	Hs
		557299 FARP1_HUMAN (239-836): 7.11e-76: 276: 13.99		PGFRA_HUMAN (3-1106): 0: 716: 42.48
+	Mm
		403536 VAV_MOUSE (297-904): 4.84e-89: 310: 15.35		KIT_MOUSE (24-1004): 0: 603: 31.01
+	Hs
		499291 VAV3_HUMAN (357-696): 3.83e-76: 273: 21.33		KIT_HUMAN (3-1003): 0: 601: 29.99
+	Hs
		548695 VAV_HUMAN (297-904): 1.46e-90: 315: 15.35		MERTK_HUMAN (120-967): 1.8e-135: 437: 16.54
+	Hs
		445884 VAV3_HUMAN (357-696): 3.83e-76: 273: 21.33		ROS1_HUMAN (118-1073): 2.6e-112: 388: 16.99
+	Hs
		508022 ITSN1_HUMAN (55-832): 2.19e-100: 356: 15.02		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		508143 ARHGQ_HUMAN (27-773): 6.23e-95: 328: 16.69		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		507829 VAV_HUMAN (297-904): 1.46e-90: 315: 15.35		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		508287 FARP1_HUMAN (239-836): 7.11e-76: 276: 13.99		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		609419 NGEF_HUMAN (171-774): 4.88e-89: 306: 16.48		FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66
+	Hs
		607984 ITSN1_HUMAN (55-832): 2.19e-100: 356: 15.02		FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73
+	Hs
		607939 FGD1_HUMAN (69-982): 1.24e-90: 317: 14.59		FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73