Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 26496610
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, CH~Filamin, CH~Spectrin
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030036 - actin cytoskeleton organization
GO:0045296 - cadherin binding
GO:0051015 - actin filament binding
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2390
Hs

1 2647
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024