HitPredict

Interactor 1: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Interactor 2: MYB (P10242)
Transcriptional activator Myb (Proto-oncogene c-Myb)
Gene: MYB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35140242, 20195357
Identification Methods	proximity labelling technology, display technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1707 Hs			1 640
+	Hs
		486845 KMT2B_HUMAN (1010-1707): 4.16e-74: 277: 22.55		MYB_HUMAN (1-640): 0: 620: 100.00
+	Hs
		486790 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		MYB_HUMAN (1-640): 0: 620: 100.00
+	Hs
		486777 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		MYB_HUMAN (1-640): 0: 620: 100.00
+	Hs
		152578 KMT2D_HUMAN (1567-1707): 6.69e-18: 93.2: 46.15		MYB_HUMAN (1-640): 0: 620: 100.00
+	Hs
		486916 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		MYBB_HUMAN (1-640): 1.35e-137: 419: 34.26
+	Hs
		486944 EZH1_HUMAN (1347-1690): 5.46e-74: 265: 18.64		MYBB_HUMAN (1-640): 1.35e-137: 419: 34.26