HitPredict

Interactor 1: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29474905
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1707 Hs			1 248
+	Hs
		683979 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Hs
		909600 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		909465 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		927084 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	At
		965377 EZA1_ARATH (1223-1701): 1.02e-65: 243: 13.72		14332_ARATH (3-248): 2.23e-144: 405: 58.47
+	Hs
		926950 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	At
		955871 CLF_ARATH (1125-1705): 1e-60: 228: 13.10		14332_ARATH (3-248): 2.23e-144: 405: 58.47
+	At
		788585 SUVR4_ARATH (1331-1703): 2.44e-63: 226: 15.15		14333_ARATH (3-247): 2.63e-144: 405: 58.30
+	Hs
		646925 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		646818 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		683376 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62
+	Hs
		904608 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		683283 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62
+	Hs
		904464 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		975227 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Hs
		297821 K0754_HUMAN (470-1148): 2.42e-24: 114: 15.45		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		297824 K0754_HUMAN (470-1148): 2.42e-24: 114: 15.45		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		982458 NSD3_HUMAN (1561-1706): 5.1e-55: 213: 30.20		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Hs
		297815 K0754_HUMAN (470-1148): 2.42e-24: 114: 15.45		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62