HitPredict

Interactor 1: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Interactor 2: ELK3 (P41970)
ETS domain-containing protein Elk-3 (ETS-related protein ERP) (ETS-related protein NET) (Serum response factor accessory protein 2) (SAP-2) (SRF accessory protein 2)
Gene: ELK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1707 Hs			1 407
+	Hs
		165681 SET1A_HUMAN (1-1707): 6.31e-168: 556: 100.00		ELF2_HUMAN (4-376): 1.62e-41: 156: 21.87
+	Hs
		165637 SET1A_HUMAN (1-1707): 6.31e-168: 556: 100.00		ELF1_HUMAN (4-377): 1.93e-37: 145: 20.78
+	Hs
		165710 SET1A_HUMAN (1-1707): 6.31e-168: 556: 100.00		ELF4_HUMAN (3-398): 1.84e-35: 139: 22.87
+	Hs
		165709 SET1A_HUMAN (1-1707): 6.31e-168: 556: 100.00		FEV_HUMAN (3-174): 3.76e-34: 129: 32.96
+	Hs
		785424 KMT2B_HUMAN (1010-1707): 4.16e-74: 277: 22.55		ELK3_HUMAN (19-407): 1.88e-65: 216: 100.00
+	Hs
		1077618 KMT2B_HUMAN (1010-1707): 4.16e-74: 277: 22.55		ELF2_HUMAN (4-376): 1.62e-41: 156: 21.87
+	Hs
		692200 KMT2B_HUMAN (1010-1707): 4.16e-74: 277: 22.55		ELF1_HUMAN (4-377): 1.93e-37: 145: 20.78
+	Hs
		975263 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		ELF2_HUMAN (4-376): 1.62e-41: 156: 21.87
+	Hs
		1304910 KMT2B_HUMAN (1010-1707): 4.16e-74: 277: 22.55		ELF4_HUMAN (3-398): 1.84e-35: 139: 22.87
+	Hs
		1304723 KMT2B_HUMAN (1010-1707): 4.16e-74: 277: 22.55		FEV_HUMAN (3-174): 3.76e-34: 129: 32.96
+	Hs
		692124 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		ELF1_HUMAN (4-377): 1.93e-37: 145: 20.78
+	Hs
		507437 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		ERG_HUMAN (3-164): 1.27e-31: 127: 37.58
+	Hs
		975312 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		FEV_HUMAN (3-174): 3.76e-34: 129: 32.96
+	Hs
		781220 NSD3_HUMAN (1561-1706): 5.1e-55: 213: 30.20		ETV3_HUMAN (4-395): 2.93e-39: 149: 23.15
+	Hs
		152583 KMT2D_HUMAN (1567-1707): 6.69e-18: 93.2: 46.15		ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87
+	Hs
		152604 KMT2D_HUMAN (1567-1707): 6.69e-18: 93.2: 46.15		ETV5_HUMAN (3-119): 5.53e-42: 156: 47.01
+	Hs
		152607 KMT2D_HUMAN (1567-1707): 6.69e-18: 93.2: 46.15		ETV4_HUMAN (3-143): 9.93e-42: 155: 40.82
+	Hs
		152681 KMT2D_HUMAN (1567-1707): 6.69e-18: 93.2: 46.15		ELF4_HUMAN (3-398): 1.84e-35: 139: 22.87
+	Hs
		152680 KMT2D_HUMAN (1567-1707): 6.69e-18: 93.2: 46.15		FEV_HUMAN (3-174): 3.76e-34: 129: 32.96
+	Hs
		152581 KMT2D_HUMAN (1567-1707): 6.69e-18: 93.2: 46.15		ERG_HUMAN (3-164): 1.27e-31: 127: 37.58