HitPredict

Interactor 1: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Interactor 2: E41L5 (Q9HCM4)
Band 4.1-like protein 5 (Erythrocyte membrane protein band 4.1-like 5)
Gene: EPB41L5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1707 Hs			1 733
+	Hs
		165715 SET1A_HUMAN (1-1707): 6.31e-168: 556: 100.00		E41LB_HUMAN (1-722): 9e-157: 479: 42.79
+	Hs
		165716 SET1A_HUMAN (1-1707): 6.31e-168: 556: 100.00		E41L1_HUMAN (18-732): 1.95e-139: 433: 25.54
+	Hs
		165602 SET1A_HUMAN (1-1707): 6.31e-168: 556: 100.00		E41L2_HUMAN (16-581): 4.94e-127: 404: 31.49
+	Hs
		165743 SET1A_HUMAN (1-1707): 6.31e-168: 556: 100.00		E41L3_HUMAN (35-727): 4.35e-125: 401: 24.54
+	Hs
		547075 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		EZRI_HUMAN (40-638): 3.48e-138: 420: 21.27
+	Hs
		640110 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		MOES_HUMAN (40-638): 9.72e-127: 390: 20.46
+	Hs
		505676 NSD3_HUMAN (1561-1706): 5.1e-55: 213: 30.20		EPB41_HUMAN (19-595): 6.95e-140: 434: 29.53
+	Hs
		297816 K0754_HUMAN (470-1148): 2.42e-24: 114: 15.45		RADI_HUMAN (40-638): 2.34e-129: 397: 21.10
+	Hs
		297842 K0754_HUMAN (470-1148): 2.42e-24: 114: 15.45		E41LA_HUMAN (40-687): 2.13e-119: 375: 27.04