HitPredict

Interactor 1: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Interactor 2: ASH2L (Q9UBL3)
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)
Gene: ASH2L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.985

The method score is based on:

Property Details
Experiments 23453808, 23870121, 27563068, 29474905, 31076518, 24981860, 16253997, 17998332, 21653943, 26886794, 34079125, 33961781, 23508102, 37974198, 20305087
Identification Methods pull down, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SET~SPRY
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0008013 - beta-catenin binding
GO:0035097 - histone methyltransferase complex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1707
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024