HitPredict

Interactor 1: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31076518
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008013 - beta-catenin binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1707 Hs			1 463
+	Mm
		1149804 Q6AXH7_MOUSE (1163-1690): 2.64e-76: 272: 14.81		RUVB2_MOUSE (1-463): 0: 718: 99.57
+	Hs
		1080488 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Hs
		203815 SUV91_HUMAN (1506-1706): 1.66e-73: 253: 22.75		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Mm
		888071 Q6AXH7_MOUSE (1163-1690): 2.64e-76: 272: 14.81		RUVB1_MOUSE (8-451): 0: 656: 42.67
+	Hs
		1080492 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Sc
		810383 SET2_YEAST (1444-1706): 3.42e-66: 241: 19.17		RUVB2_YEAST (7-451): 0: 650: 68.76