HitPredict

Interactor 1: N4BP3 (O15049)
NEDD4-binding protein 3 (N4BP3)
Gene: N4BP3

Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	31527615, unassigned1953
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 544 Hs			1 595
+	Hs
		370319 LZTS2_HUMAN (4-540): 6.23e-42: 161: 25.63		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		370586 ITSN2_HUMAN (226-543): 6.34e-16: 83.5: 9.22		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		370819 MRCKB_HUMAN (180-541): 6.28e-15: 80.4: 11.43		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		369789 MRCKA_HUMAN (207-541): 3.18e-14: 78.1: 12.70		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		370120 MY18A_HUMAN (253-540): 1.68e-10: 66.2: 13.00		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		1269479 LZTS2_HUMAN (4-540): 6.23e-42: 161: 25.63		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		433179 LAMB1_HUMAN (157-544): 3.34e-39: 155: 13.97		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		230546 LZTS3_HUMAN (98-527): 1.43e-35: 143: 26.95		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		377814 LZTS1_HUMAN (12-530): 5.36e-39: 152: 25.81		GCR_HUMAN (5-557): 4.67e-109: 346: 22.51
+	Hs
		1269784 ITSN2_HUMAN (226-543): 6.34e-16: 83.5: 9.22		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		1270038 MRCKB_HUMAN (180-541): 6.28e-15: 80.4: 11.43		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		1051388 DCTN1_HUMAN (146-543): 2.49e-14: 78.5: 13.97		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		1150622 MRCKG_HUMAN (334-543): 4.08e-11: 68.1: 14.35		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Mm
		1142657 FKB15_MOUSE (44-540): 4.25e-29: 124: 11.22		ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42
+	Hs
		377746 ITSN2_HUMAN (226-543): 6.34e-16: 83.5: 9.22		GCR_HUMAN (5-557): 4.67e-109: 346: 22.51
+	Hs
		659748 MRCKB_HUMAN (180-541): 6.28e-15: 80.4: 11.43		RXRB_HUMAN (144-549): 1.9e-111: 345: 27.64
+	Hs
		487504 MRCKA_HUMAN (207-541): 3.18e-14: 78.1: 12.70		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		487786 MYO5C_HUMAN (197-521): 8.07e-13: 73.5: 6.73		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		487519 MRCKG_HUMAN (334-543): 4.08e-11: 68.1: 14.35		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		487627 MY18A_HUMAN (253-540): 1.68e-10: 66.2: 13.00		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16