HitPredict

Interactor 1: KDM6B (O15054)
Lysine-specific demethylase 6B (EC 1.14.11.68) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3) (Lysine demethylase 6B) ([histone H3]-trimethyl-L-lysine(27) demethylase 6B)
Gene: KDM6B

Interactor 2: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1643 Hs			1 709
+	Hs
		996722 ANR11_HUMAN (442-1102): 2.07e-16: 88: 19.13		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996965 SRRM2_HUMAN (324-1330): 8.25e-13: 76.1: 10.52		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		165827 KDM6B_HUMAN (1-1643): 3.88e-172: 565: 100.00		SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31
+	Hs
		183091 KDM6A_HUMAN (1-647): 1.77e-50: 199: 14.24		SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93
+	Hs
		183081 KDM6A_HUMAN (1-647): 1.77e-50: 199: 14.24		SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15
+	Hs
		183160 KDM6A_HUMAN (1-647): 1.77e-50: 199: 14.24		SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61
+	Hs
		183046 KDM6A_HUMAN (1-647): 1.77e-50: 199: 14.24		SOX15_HUMAN (513-702): 2.03e-33: 130: 15.10
+	Hs
		183080 KDM6A_HUMAN (1-647): 1.77e-50: 199: 14.24		SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31
+	Hs
		1270803 CBP_HUMAN (35-1003): 1.04e-25: 118: 11.05		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		818828 CBP_HUMAN (35-1003): 1.04e-25: 118: 11.05		SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15
+	Mm
		57642 EP300_MOUSE (26-1033): 9.84e-31: 135: 8.89		A2AWT7_MOUSE (355-708): 5.83e-25: 112: 10.61
+	Hs
		617349 CBP_HUMAN (35-1003): 1.04e-25: 118: 11.05		SP100_HUMAN (486-629): 1.52e-24: 111: 28.86
+	Hs
		818819 KMT2C_HUMAN (238-1185): 1.59e-12: 75.2: 12.41		SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15
+	Hs
		1243843 KMT2C_HUMAN (238-1185): 1.59e-12: 75.2: 12.41		SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61
+	Hs
		225805 SRRM2_HUMAN (324-1330): 8.25e-13: 76.1: 10.52		SOX15_HUMAN (513-702): 2.03e-33: 130: 15.10
+	Hs
		311835 TACC2_HUMAN (37-1295): 1.03e-09: 66.1: 9.51		HM20B_HUMAN (508-709): 6.25e-36: 139: 18.81
+	Hs
		818266 KMT2C_HUMAN (238-1185): 1.59e-12: 75.2: 12.41		SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31
+	Hs
		643378 CBP_HUMAN (35-1003): 1.04e-25: 118: 11.05		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		449782 CBP_HUMAN (35-1003): 1.04e-25: 118: 11.05		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04
+	Hs
		449842 SRRM2_HUMAN (324-1330): 8.25e-13: 76.1: 10.52		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04