Interactor 1: KDM6B (O15054)
Lysine-specific demethylase 6B (EC 1.14.11.68) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3) (Lysine demethylase 6B) ([histone H3]-trimethyl-L-lysine(27) demethylase 6B)
Gene: KDM6B

Interactor 2: KDM7A (Q6ZMT4)
Lysine-specific demethylase 7A (JmjC domain-containing histone demethylation protein 1D) (Lysine-specific demethylase 7) ([histone H3]-dimethyl-L-lysine9 demethylase 7A) (EC 1.14.11.65)
Gene: KDM7A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 30224337, 24981860
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains JHD~JmjC, JmjC~JmjC, JmjC~PHD
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032452 - histone demethylase activity
GO:0071558 - histone H3K27me2/H3K27me3 demethylase activity
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1643
Hs

1 941
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024