HitPredict

Interactor 1: SYNEM (O15061)
Synemin (Desmuslin)
Gene: SYNM

Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	15872089
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1565 Hs			1 906
+	Mm
		610615 SYNEM_MOUSE (1-1555): 0: 1154: 69.14		CBL_MOUSE (1-906): 0: 888: 91.59
+	Hs
		359303 K1C14_HUMAN (9-349): 1.21e-141: 446: 23.98		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610361 K1C17_HUMAN (6-328): 7.11e-138: 434: 26.54		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		445005 K1C16_HUMAN (7-336): 6.38e-136: 430: 25.68		CBL_HUMAN (1-906): 0: 917: 100.00
+	Mm
		57585 SYNEM_MOUSE (1-1555): 0: 1154: 69.14		TITIN_MOUSE (519-901): 4.44e-10: 66.1: 8.73
+	Hs
		610433 K2C79_HUMAN (3-325): 5.66e-65: 232: 18.65		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610295 K2C6C_HUMAN (4-325): 4.14e-61: 222: 19.44		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		380445 K2C6B_HUMAN (4-325): 6.21e-61: 221: 19.44		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		531534 K2C5_HUMAN (4-325): 2.24e-60: 220: 18.83		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		359466 K2C6A_HUMAN (4-325): 1.18e-59: 218: 19.44		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		443330 VIME_HUMAN (11-320): 2.95e-31: 131: 33.44		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610513 KRT84_HUMAN (220-525): 2.17e-09: 64: 8.75		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		444454 K1C19_HUMAN (6-330): 8.56e-134: 421: 23.01		ASPP1_HUMAN (445-844): 1.47e-10: 67.3: 10.25
+	Hs
		203200 VIME_HUMAN (11-320): 2.95e-31: 131: 33.44		SYNJ1_HUMAN (542-897): 2.72e-14: 79.6: 10.22
+	Hs
		203211 PERI_HUMAN (11-320): 1.18e-22: 105: 31.83		SYNJ1_HUMAN (542-897): 2.72e-14: 79.6: 10.22
+	Hs
		781964 PERI_HUMAN (11-320): 1.18e-22: 105: 31.83		ASPP1_HUMAN (445-844): 1.47e-10: 67.3: 10.25