HitPredict

Interactor 1: DCLK1 (O15075)
Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)
Gene: DCLK1

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26638075, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007399 - nervous system development
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 1278
+	Hs
		1051364 DCLK2_HUMAN (1-725): 0: 801: 66.22		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		166615 DCLK1_HUMAN (1-740): 0: 896: 100.00		KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85
+	Hs
		681840 AKT1_HUMAN (304-706): 2.75e-132: 402: 24.22		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		1051522 KCC2A_HUMAN (387-648): 1.19e-64: 224: 42.48		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		725229 M3K3_HUMAN (51-646): 5.47e-139: 424: 18.59		MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13
+	Hs
		681975 AKT1_HUMAN (304-706): 2.75e-132: 402: 24.22		CLIP3_HUMAN (10-139): 7.2e-31: 131: 31.34
+	Mm
		82707 AKT1_MOUSE (304-706): 4.56e-132: 401: 24.22		CLIP3_MOUSE (29-139): 1.07e-27: 121: 34.51
+	Hs
		724983 M3K3_HUMAN (51-646): 5.47e-139: 424: 18.59		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		681696 AKT1_HUMAN (304-706): 2.75e-132: 402: 24.22		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		551616 AKT1_HUMAN (304-706): 2.75e-132: 402: 24.22		DESP_HUMAN (227-1049): 1.36e-14: 81.5: 14.64