Interactor 1: DCLK1 (O15075)
Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)
Gene: DCLK1

Interactor 2: MELK (Q14680)
Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)
Gene: MELK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27173435
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains KA1~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0106310 - protein serine kinase activity
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 740
Hs

1 651
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Hs
+ At
+ Hs
+ At
+ At
+ At
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024