HitPredict

Interactor 1: DCLK1 (O15075)
Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)
Gene: DCLK1

Interactor 2: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 1491
+	Hs
		1021556 M3K3_HUMAN (51-646): 5.47e-139: 424: 18.59		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Mm
		292336 DCX_MOUSE (6-359): 2.77e-137: 410: 69.89		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Hs
		1050040 M3K3_HUMAN (51-646): 5.47e-139: 424: 18.59		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Mm
		1143346 KCC2D_MOUSE (385-737): 1.46e-130: 398: 33.05		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Hs
		681891 AKT1_HUMAN (304-706): 2.75e-132: 402: 24.22		NHRF3_HUMAN (475-719): 9.38e-14: 77.7: 23.08
+	Mm
		250629 KCC2D_MOUSE (385-737): 1.46e-130: 398: 33.05		LNX1_MOUSE (13-275): 5.63e-14: 79.1: 11.28
+	Dm
		677687 KCC2A_DROME (385-726): 1.44e-126: 388: 34.97		DLG1_DROME (2-319): 1.1e-10: 68.7: 11.32
+	Mm
		1143553 KS6A2_MOUSE (388-680): 2.2e-99: 324: 27.24		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Mm
		515234 KCC2A_MOUSE (387-648): 1.01e-64: 224: 42.48		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Mm
		1131547 Q5SVI3_MOUSE (387-647): 4.1e-63: 221: 43.77		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Hs
		1271040 KCC2A_HUMAN (387-648): 1.19e-64: 224: 42.48		DLG3_HUMAN (16-556): 6.49e-16: 85.6: 12.05
+	Hs
		1021591 KCC2A_HUMAN (387-648): 1.19e-64: 224: 42.48		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Mm
		659457 KCC2B_MOUSE (387-647): 3.22e-62: 219: 43.77		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Rn
		506740 KCC2A_RAT (387-648): 1.01e-64: 224: 42.48		DLG1_RAT (14-119): 3.08e-14: 80.2: 16.22
+	Rn
		506744 KCC2A_RAT (387-648): 1.01e-64: 224: 42.48		DLG3_RAT (16-556): 1.09e-13: 78.3: 11.75
+	Mm
		515236 KCC2A_MOUSE (387-648): 1.01e-64: 224: 42.48		INADL_MOUSE (1067-1253): 2.44e-12: 74.4: 17.62
+	Mm
		659459 KCC2B_MOUSE (387-647): 3.22e-62: 219: 43.77		INADL_MOUSE (1067-1253): 2.44e-12: 74.4: 17.62