HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2479 Hs			1 1130
+	Hs
		325935 MYH2_HUMAN (1112-2207): 2.43e-34: 147: 11.01		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325737 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325608 MYH1_HUMAN (1-813): 5.08e-33: 143: 11.14		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325605 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325609 MYH7_HUMAN (1748-2477): 7.64e-28: 126: 13.78		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325612 MYH8_HUMAN (1853-2477): 2.16e-24: 115: 9.15		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325955 MYH4_HUMAN (1686-2474): 3.39e-17: 91.4: 11.60		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325611 MYH6_HUMAN (1960-2477): 2.09e-15: 85.4: 11.32		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325936 MYH13_HUMAN (3-559): 1.15e-13: 79.7: 12.21		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325867 AKAP9_HUMAN (83-717): 1.65e-12: 75.8: 10.19		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		149340 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		LATS2_HUMAN (13-1121): 0: 751: 49.61
+	Hs
		610795 MYH2_HUMAN (1112-2207): 2.43e-34: 147: 11.01		KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58
+	Hs
		522538 MYH1_HUMAN (1-813): 5.08e-33: 143: 11.14		KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58
+	Hs
		551616 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50
+	Mm
		682109 GRDN_MOUSE (111-1021): 3.88e-11: 71.4: 16.68		AKT1_MOUSE (595-1081): 6.22e-141: 435: 24.50
+	Mm
		1130947 GRDN_MOUSE (111-1021): 3.88e-11: 71.4: 16.68		AKT2_MOUSE (603-1081): 2.58e-139: 431: 25.81
+	Hs
		610802 MYH4_HUMAN (1686-2474): 3.39e-17: 91.4: 11.60		KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58
+	Hs
		568780 AKAP9_HUMAN (83-717): 1.65e-12: 75.8: 10.19		KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59
+	Hs
		528359 MYH6_HUMAN (1960-2477): 2.09e-15: 85.4: 11.32		KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58
+	Hs
		610775 AKAP9_HUMAN (83-717): 1.65e-12: 75.8: 10.19		KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58